发明名称 |
METHOD FOR DIAGNOSING LIVER FIBROSIS |
摘要 |
A method for the detection of the presence and/or the severity of a liver disease in a patient comprising measuring in an isolated sample TIMP-1 (tissue inhibitor of metalloproteinase I), ferritin, at least one additional parameter selected from the group consisting of A2M (alpha-2-macroglobulin) and PI (prothrombin index) and optionally measuring at least one additional biochemical or clinical parameter and diagnosing the presence and/or severity of a liver disease based on the presence or measured levels of these parameters. The method can be used for monitoring therapeutic treatment of liver fibrosis and staging of liver fibrosis.
|
申请公布号 |
US2007178442(A1) |
申请公布日期 |
2007.08.02 |
申请号 |
US20070673058 |
申请日期 |
2007.02.09 |
申请人 |
WIENHUES-THELEN URSULA-HENRIKE;CALES PAUL;HUEDIG HENDRIK |
发明人 |
WIENHUES-THELEN URSULA-HENRIKE;CALES PAUL;HUEDIG HENDRIK |
分类号 |
C12Q1/00;C12Q1/37 |
主分类号 |
C12Q1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|