发明名称 |
TRIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 |
摘要 |
Triazole derivatives of structural formula I are selective inhibitors of the 11ß-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM. |
申请公布号 |
WO2007087150(A2) |
申请公布日期 |
2007.08.02 |
申请号 |
WO2007US00351 |
申请日期 |
2007.01.09 |
申请人 |
MERCK & CO., INC.;KEVIN, NANCY, J.;GU, XIN;WADDELL, SHERMAN, T. |
发明人 |
KEVIN, NANCY, J.;GU, XIN;WADDELL, SHERMAN, T. |
分类号 |
A61K31/4196 |
主分类号 |
A61K31/4196 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|