发明名称 |
THERAPEUTIC USES OF STEROIDAL COMPOUNDS |
摘要 |
<p>A steroid derivative compound of formula (I) in which: one of R<SUP>1</SUP> and R<SUP>2</SUP> is hydroxy and the other is hydrogen; or R<SUP>1</SUP> and R<SUP>2</SUP> together represent oxo; R<SUP>3</SUP> is hydrogen or hydroxy; and the dotted lines represent single or double carbon-carbon bonds; and pharmaceutically acceptable salts and esters thereof are useful for the prevention or treatment of pain, for improving nerve regeneration after nerve injury or damage or disease, for the prevention or treatment of brain injury, damage or disease and for neuroprotection. Particularly useful compounds are 11-hydroxy-?4-androstene-3,17-dione and 11-oxo-?4-androstene-3,17-dione or their derivatives.</p> |
申请公布号 |
WO2007057691(A3) |
申请公布日期 |
2007.08.02 |
申请号 |
WO2006GB04305 |
申请日期 |
2006.11.17 |
申请人 |
HUNTER-FLEMING LIMITED;WUELFERT, ERNST;MURRAY, JAMES, ROBERT;WYNICK, DAVID |
发明人 |
WUELFERT, ERNST;MURRAY, JAMES, ROBERT;WYNICK, DAVID |
分类号 |
A61K31/568;A61K31/573;A61P25/00;A61P29/00 |
主分类号 |
A61K31/568 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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