发明名称 |
COMPARTMENTALISED COMBINATORIAL CHEMISTRY BY MICROFLUIDIC CONTROL |
摘要 |
The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules. |
申请公布号 |
EP1812156(A1) |
申请公布日期 |
2007.08.01 |
申请号 |
EP20050792864 |
申请日期 |
2005.10.12 |
申请人 |
MEDICAL RESEARCH COUNCIL;THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
GRIFFITHS, ANDREW;WEITZ, DAVID;LINK, DARREN;AHN, KEUNHO;BIBETTE, JEROME |
分类号 |
B01J19/00;C07K1/04;G01N33/543 |
主分类号 |
B01J19/00 |
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