发明名称 N-N-ACYLOXYPROPYL LYSINE METHYL ESTER- AND N,N-BIS(N- ACYLOXYPROPYL)LYSINE METHYL ESTER-TYPE COMPOUNDS AND USE THEREOF AS SURFACE-ACTIVE AGENTS WITH AN ANTIMICROBIAL ACTIVITY
摘要 The invention relates to novel compounds having an amphiphilic character (cationic, anionic, amphoteric and non-ionic), derivatives of n acyloxypropyl-type lysine amino acid according to general formula (I), which are intended to be used in the food, pharmaceutical and cosmetic industries as surface-active agents having a self-aggregating capacity and antimicrobial properties. Variations in activity are a function of the ionic nature of the final molecule, the number of fatty chains and the length thereof. The aforementioned products are prepared using a chemical synthesis method. The intermediate and final products are purified by means of liquid/liquid and liquid/solid extractions, crystallisations, cationic exchange chromatography and normal phase chromatography.
申请公布号 EP1813600(A1) 申请公布日期 2007.08.01
申请号 EP20050825290 申请日期 2005.11.16
申请人 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS 发明人 PEREZ MUNOZ, LOURDES;PINAZO GASSOL, AURORA;INFANTE MARTINEZ-PARDO, MARIA ROSA;ANGELET SUBIRATS, MARTA
分类号 C07C229/26;A61K31/221;C11D1/46 主分类号 C07C229/26
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