发明名称 |
SOLUBLE PROTEIN AND UTILIZATION OF THE SAME |
摘要 |
<p>The present invention relates to a method for screening a medicine using a protein, and a compound obtained by the screening method. A compound or a salt thereof inhibiting activity or expression of the protein of the present invention, a neutralizing antibody against the protein, a polynucleotide that are complementary to a polynucleotide coding the protein, and the like can be used as an agent for preventing and/or treating neurodegenerative diseases and the like. Moreover, a compound or a salt thereof enhancing activity or expression of the protein of the present invention, the protein or a partial peptide thereof, a polynucleotide coding the protein, and the like can be used as an agent for preventing and/or treating cancers and the like. Furthermore, the protein of the present invention is useful as a reagent for screening a compound inhibiting or enhancing activity of the protein.</p> |
申请公布号 |
EP1813671(A1) |
申请公布日期 |
2007.08.01 |
申请号 |
EP20050807110 |
申请日期 |
2005.11.18 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
TADA, HIDEAKI;BANDO, TOMOYUKI;HAYASHI, AKIO |
分类号 |
C12N15/00;A61K45/00;A61P9/10;A61P25/28;A61P29/00;A61P37/08;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/16;C12N15/09;C12P21/00;C12Q1/44 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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