发明名称 Method for preparing polymeric matrices by radiation in the presence of sensitive pharmaceutical compounds
摘要 <p>The present invention relates to a method for the preparation of a drug loaded matrix with a pharmaceutical compound by polymerizing a polymerisation mixture by radiation in the presence of at least one sensitive pharmaceutical compound, wherein the polymerisation mixture comprises a) at least one polymerisable compound b) optionally at least one photoinitiator c) optionally at least one additive which are chosen such that the sensitive pharmaceutical compound is degraded less than 2%, or which are chosen such that the sensitive pharmaceutical compound is protected against degradation such that the degradation is about 50% or less when compared to radiation with a constituent that produce radicals.</p>
申请公布号 EP1813268(A1) 申请公布日期 2007.08.01
申请号 EP20060012347 申请日期 2006.06.15
申请人 DSM IP ASSETS B.V. 发明人
分类号 A61K9/16;A61K9/51 主分类号 A61K9/16
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