摘要 |
<p>The present invention relates to a method for the preparation of a drug loaded matrix with a pharmaceutical compound by polymerizing a polymerisation mixture by radiation in the presence of at least one sensitive pharmaceutical compound, wherein the polymerisation mixture comprises
a) at least one polymerisable compound
b) optionally at least one photoinitiator
c) optionally at least one additive
which are chosen such that the sensitive pharmaceutical compound is degraded less than 2%, or which are chosen such that the sensitive pharmaceutical compound is protected against degradation such that the degradation is about 50% or less when compared to radiation with a constituent that produce radicals.</p> |