Stable combination of active agents containing glucose derivates and hydroxycarboxylic acids

摘要

Emulsions buffered to a pH of 5.5 or less comprise an alpha -hydroxy acid (I) and two surfactants, namely a glucose derivative (II) and a polyglycerol derivative (III). Emulsions buffered to a pH of 5.5 or less comprise an alpha -hydroxy acid of formula (I) and two surfactants, namely a glucose derivative of formula (II) and a polyglycerol derivative of formula (III). R'-CR"(OH)-COOX (I) G-O-CO-R (II) R3O(CH2CH(OR4)CH2O)nR5 (III) R', R" : H; 1-25C alkyl; 1-25C alkyl substituted with COOH, OH, CHO and/or oxo; phenyl; or phenyl substituted with COOH, OH and/or 1-25C alkyl; or CR'R" = 3-7C cycloalkylidene optionally substituted with COOH, OH, oxo and/or 1-25C alkyl; X : H, Me, Et or a salt-forming cation; G : a 1-O-R1-2-O-R2-6-deoxyglucose residue; R : 1-24C alkyl; R1, R2H or 1-24C alkyl; R3-R5H or 8-24C (un)saturated fatty acid residues optionally substituted with 1-3 OH groups; n : 2-8. ACTIVITY : Dermatological; Antiseborrheic. MECHANISM OF ACTION : None given.