发明名称 |
Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams |
摘要 |
Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a nitro group. Screening data shows antimicrobial activity against various bacterial cell lines, particularly gram-positive bacteria, and anti-cancer activity.
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申请公布号 |
US7250438(B2) |
申请公布日期 |
2007.07.31 |
申请号 |
US20050146613 |
申请日期 |
2005.06.06 |
申请人 |
NEREUS PHARMACEUTICALS, INC. |
发明人 |
MANAM RAMA RAO;POTTS BARBARA C. |
分类号 |
A61K31/407;C07D491/00;C07D491/10;C07D491/107 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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