Verfahren zur Herstellung von Disulfidbindungen bei zyklischen Peptiden

摘要

A non-oxidative process is described for the formation of an intramolecular disulfide bond in precursors of the peptide or peptidomimetic type; said process comprises the preparation of a linear intermediate containing an -SH group in the S-sulfonate form and a second -SH group which is obtainable in the free form by means of acid treatment.