<p>The present invention relates to an isomerisation method of vitamin D analogues, such as compounds useful for the synthesis of calcipotriol, and to and to the use of a flow- through photoreactor or continuous flow photoreactor reactor for making said vitamin D analogues. The present invention relates further to the use of intermediates produced with said method for making calcipotriol or calcipotriol monohydrate, or pharmaceutical formulations thereof.</p>
申请公布号
WO2007082533(A1)
申请公布日期
2007.07.26
申请号
WO2006DK00244
申请日期
2006.05.08
申请人
LEO PHARMA A/S;FOLKMANN, MICHAEL, PETER;HANSEN, ERIK, TOMGAARD