SOLID FORMS OF A PYRROLOPYRIMIDINE DERIVATIVE AND THEIR USE AS ANTI-TUMOR AGENTS

摘要

The invention relates to new crystalline forms of {6-[4-{4-ethyl-piperazin-1 -ylmethyl)- phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1-phenyl-ethyl)-amine, the process for the preparation of these crystalline forms of {6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H- pyrrolo[2,3-d]pyrimidin-4-yl}-((R)-1 -phenyl-ethyl)-amine, compositions containing these crystalline forms of {6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d ]pyrimidin-4-yl}-((R)-1-phenyl-ethyl)-amine, and the use of these crystalline forms of {6-[4-(4-ethyl- piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-{(R)-1-phenyl-ethyl)-amine in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans.