发明名称 |
Secretion, transcription and sporulation genes in Bacillus clausii |
摘要 |
The present invention relates to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms having exogenous nucleic acid sequences introduced therein and methods for producing proteins in such host cells, such as members of the genus Bacillus. More specifically, the present invention relates to the expression, production and secretion of a polypeptide of interest and to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention provides for the enhanced expression of a selected polypeptide by a microorganism.
|
申请公布号 |
US2007172922(A1) |
申请公布日期 |
2007.07.26 |
申请号 |
US20070725900 |
申请日期 |
2007.03.19 |
申请人 |
FERRARI EUGENIO;VAN KIMMENADE ANITA |
发明人 |
FERRARI EUGENIO;VAN KIMMENADE ANITA |
分类号 |
C12N15/09;C12P21/06;C07H21/04;C07K14/32;C12N1/21;C12N9/48;C12N9/54;C12N15/74;C12P21/02;C12Q1/68;C12R1/07 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|