发明名称 |
PARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR |
摘要 |
<p>The present invention is directed to novel pharmaceutical compositions comprising nano- and micro-particulate formulations of poorly water soluble tubulin inhibitors of the indole chemical class, preferably N-substituted indol-3-glyoxyamides, and more preferably N-(Pyridin-4-yl)-[1-(4-chlorobenzyl)-indol-3-yl]glyoxylic acid amide (D-24851), also known as "Indibulin," and methods of making and using such compositions for the treatment of anti-tumor agent resistant cancers and other diseases.</p> |
申请公布号 |
EP1809279(A1) |
申请公布日期 |
2007.07.25 |
申请号 |
EP20050851355 |
申请日期 |
2005.11.03 |
申请人 |
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A. |
发明人 |
PAPADOPOULOS, PAVLOS;DOTY, MARK;KIPP, JAMES E.;ROESSLER, BERTHOLD |
分类号 |
A61K31/404;A61K9/00;A61P35/00 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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