发明名称 |
Method for screening crystallization conditions in protein solution crystal growth |
摘要 |
A method of screening protein crystal growth conditions with picogram to microgram amounts of protein in picoliter or nanoliter volumes is provided. A preferred method comprises a microarray with a plurality of micro-chambers in the microarray. A protein solution is placed into the micro-chambers by an automated dispensing mechanism. The protein crystal growth conditions of each of the micro-chambers is adjusted so that the protein crystal growth conditions in at least two of the micro-chambers differs. Crystallization of the protein solution in the micro-chambers is effected. Protein crystal growth in the micro-chambers is then observed. |
申请公布号 |
EP1701159(A3) |
申请公布日期 |
2007.07.25 |
申请号 |
EP20060075121 |
申请日期 |
2000.04.05 |
申请人 |
UNIVERSITY OF ALABAMA |
发明人 |
DELUCAS, LAWRENCE J.;BRAY, TERRY L. |
分类号 |
G01N31/00;C30B7/00;G01N33/00 |
主分类号 |
G01N31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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