PROCESS FOR THE PREPARATION OF COMPOUND WITH POTENTIAL PHYSIOLOGICAL PROPERTIES OF 1,1-DIETHYLCARBOXY-2-TRIFLUOROMETHYL-2-(2'-BENZIMIDAZOLYL)-ETHYLENE

摘要

A process for the preparation of compound with potential physiological properties of 1,1-diethylcarboxy-2-trifluoromethyl-2-(2'-benzimidazolyl)-ethylene comprises the reaction of nucleophilic substitution between 2-benzimidazolol which acts as nucleophile and 1,1-diethylcarboxy-2-chloro-2-trifluoromethylethylene, in the molecule of which chlorine atom is activated by two diethylcarboxy-groups in the system of anhydrous solvents (benzol-dimethylformamide) in the presence of triethylamine as dehalogenating agent.