发明名称 A NUCLEIC ACID MOLECULE ENCODING AN A ??-ANTIBODY CHAIN AND METHODS AND COMPOSITIONS FOR IMPROVING RECOMBINANT PROTEIN PRODUCTION
摘要 Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.
申请公布号 IL182182(D0) 申请公布日期 2007.07.24
申请号 IL20070182182 申请日期 2007.03.26
申请人 WYETH;ELAN PHARMA INTERNATIONAL LTD.;NEURALAB LIMITED 发明人
分类号 C07K 主分类号 C07K
代理机构 代理人
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