发明名称 Gamma-aminoamide modulators of chemokine receptor activity
摘要 The present invention is directed to compounds of the formula (I), wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>11</SUP>, R<SUP>12</SUP>, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
申请公布号 US7247725(B2) 申请公布日期 2007.07.24
申请号 US20050528329 申请日期 2005.03.18
申请人 MERCK & CO., INC. 发明人 BUTORA GABOR;PASTERNAK ALEXANDER;YANG LIHU;ZHOU CHANGYOU
分类号 C07D221/20;A61K31/438;A61K31/445;A61K31/4747;A61K31/505;C07D211/20;C07D211/52;C07D401/04;C07D413/04;C07D417/04 主分类号 C07D221/20
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