发明名称 ANTIBODIES DIRECTED TO ANGIOPOIETIN-2 AND USES THEREOF.
摘要 <p>Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementary determining regions (CDR s), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobin molecules and monoclonal antibodies.</p>
申请公布号 MX2007007484(A) 申请公布日期 2007.07.20
申请号 MX20070007484 申请日期 2005.12.19
申请人 ASTRAZENECA AB 发明人 STEPHEN CHARLES EMERY;LARRY L. GREEN;QING ZHOU;BRUCE A. KEYT;XIAO-DONG YANG;DAVID C. BLAKEY
分类号 C07K16/22;C07K16/28 主分类号 C07K16/22
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