发明名称 BISARYLUREA DERIVATIVES USEFUL FOR INHIBITING CHK1.
摘要 <p>Aryl- and heteroaryl-substituted urea compounds useful in the treatment ofdiseases and conditions related to DNA damage or lesions in DNA replication aredisclosed. Methods of making the compounds, and their use as therapeutic agents,for example, in treating cancer and other diseases characterized by defectsin DNA replication, chromosome segregation, or cell division also are disclosed.Formula (I).</p>
申请公布号 MX2007000259(A) 申请公布日期 2007.07.20
申请号 MX20070000259 申请日期 2005.06.24
申请人 ICOS CORPORATION 发明人 STEPHEN T. SCHLACHTER;LAURENCE EDWARD BURGESS;JOHN JOSEPH GAUDINO;ADAM WADE COOK;KIMBA L. FISCHER
分类号 C07D241/20;C07D401/12;C07D405/14 主分类号 C07D241/20
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