| 发明名称 |
3-[2-(3-ACYLAMINO-2-OXO-2H-PYRIDIN-1-YL)-ACETYLAMINO]-4-OXO-PENT ANOIC ACID DERIVATIVES AND THEIR USE AS CASPASE INHIBITORS. |
| 摘要 |
<p>The present invention provides a compound of formula (I): wherein R1, R2,R3,R4,and R5 are as definedherein. The present invention also provides pharmaceutical compositions andmethods using such compositions for treating a caspase-mediated diseases andprocesses for preparing the compounds of the invention.</p> |
| 申请公布号 |
MX2007006258(A) |
申请公布日期 |
2007.07.20 |
| 申请号 |
MX20070006258 |
申请日期 |
2005.11.21 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED. |
发明人 |
MICHAEL MORTIMORE;JOHN R. STUDLEY;JEAN-DAMIEN CHARRIER;RONALD KNEGTEL |
| 分类号 |
A61K31/4436;A61K31/4439;C07D213/75;C07D401/06;C07D409/06 |
主分类号 |
A61K31/4436 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
