| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicine showing a further high antitumor activity and excellent in safety. SOLUTION: This medicine contains a compound expressed by general formula (1) [wherein, X<SB>1</SB>is N or -CH=; R<SP>1</SP>is -Z-R<SP>6</SP>; Z is -CO-, -CH(OH)- or the like; R<SP>6</SP>is a 5 to 15-membered saturated or unsaturated heterocyclic ring group such as a single ring, bicyclic ring or tricyclic ring having 1-4 N, O or S, or the like; R<SP>2</SP>is H or a halogen atom; Y is -O-, -CO-, -CH(OH)-, a lower alkylene or the like; A is a group of chemical formula 6 or the like; R<SP>3</SP>is H, a lower alkoxy or the like; (p) is 1 or 2; and R<SP>4</SP>is an imidazolyl lower alkyl or the like] or its salt as an active ingredient. COPYRIGHT: (C)2007,JPO&INPIT
|
