发明名称 HMGCOA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF
摘要 The invention provides a compound comprising a first pharmacological moiety connected to at least a second pharmacological moiety through a physiologically labile linker, or a salt thereof. The invention also provides a method of reducing cardiovascular disease or cardiovascular disease-related conditions in an individual. The method involves administering to an individual with cardiovascular disease an effective amount of a compound, in which the compound has a first pharmacological moiety linked to a second pharmacological moiety, and the compound or either or both of the constituent pharmacological moieties acts to reduce, treat, or prevent cardiovascular disease. The compounds of the invention can be delivered in a drug delivery device.
申请公布号 WO2006110882(A3) 申请公布日期 2007.07.19
申请号 WO2006US13907 申请日期 2006.04.12
申请人 PSIVIDA INC.;ASHTON, PAUL;CYNKOWSKA, GRAZYNA;CYNKOWSKI, TADEUSZ;SMITH, THOMAS, J. 发明人 ASHTON, PAUL;CYNKOWSKA, GRAZYNA;CYNKOWSKI, TADEUSZ;SMITH, THOMAS, J.
分类号 A61K47/48 主分类号 A61K47/48
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