| 摘要 |
<p>The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.</p> |
| 申请人 |
SEPRACOR INC. |
发明人 |
CAMPBELL, UNA;MA, JIANGUO;BUSH, LARRY R.;ENGEL, SHARON RAE;HARDY, LARRY WENDELL;WANG, FENGJIANG;VARNEY, MARK A.;HEWITT, MICHAEL CHARLES;KOCH, PATRICK;SHAO, LIMING;MALCOLM, SCOTT CHRISTOPHER;CAMPBELL, JOHN E. |
