发明名称 |
ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS |
摘要 |
Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
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申请公布号 |
WO2007041052(B1) |
申请公布日期 |
2007.07.19 |
申请号 |
WO2006US37196 |
申请日期 |
2006.09.25 |
申请人 |
MERCK & CO., INC.;JIAN, TIANYING;LIU, JIAN;NARGUND, RAVI, P. |
发明人 |
JIAN, TIANYING;LIU, JIAN;NARGUND, RAVI, P. |
分类号 |
C07D471/10;A61K31/4355;A61K31/5386;A61P3/00;A61P15/00;C07D493/20;C07D498/08 |
主分类号 |
C07D471/10 |
代理机构 |
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