发明名称 |
Specific antagonists for glucose-dependent insulinotropic polypeptide (GIP) |
摘要 |
In one embodiment, this invention provides an antagonist of glucose-dependent insulinotropic polypeptide (GIP) consisting essentially of a 24 amino acid polypeptide corresponding to positions 7-30 of the sequence of GIP. In another embodiment, this invention provides a method of preventing and treating obesity and non-insulin dependent diabetes mellitus (Type II) in a patient comprising administering to the patient an antagonist of glucose-dependent insulinotropic polypeptide (GIP). In yet another embodiment, this invention provides a method of improving glucose tolerance in a mammal comprising administering to the mammal an antagonist of glucose-dependent insulinotropic polypeptide (GIP).
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申请公布号 |
US2007167374(A1) |
申请公布日期 |
2007.07.19 |
申请号 |
US20060504535 |
申请日期 |
2006.08.15 |
申请人 |
WOLFE M M;TSENG CHI-CHUAN;NEVILLE LINDA |
发明人 |
WOLFE M. M.;TSENG CHI-CHUAN;NEVILLE LINDA |
分类号 |
A61K38/26;A61K38/00;C07K14/605 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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