SUBSTITUTED PYRIMIDINONES

摘要

Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R₁, R₂, R₄, and R₅ are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.