Method of MR imaging

摘要

The invention provides, in a method of perfusion magnetic resonance imaging of a region of interest in a vascularized animal subject, said method comprising administering a contrast agent bolus into the vascular system of said subject; determining the magnetic resonance signal strength s_i(t) for voxels (i) of said region of interest at a series of time values (t) over a period from before contrast agent arrival in said region of interest to at least the end of the first pass of said contrast agent through said region of interest; from the determined values s_i(t) for said signal strength and an arterial input function v(t), determining values for the tissue residue function r_i(t) for each said voxel; and optionally generating an image of said region of interest from the determined values of r_i(t); the improvement comprising generating from s_i(t) a voxel specific arterial function v_i(t) and using said voxel specific arterial function to determine the values of the tissue residue function r_i(t).