发明名称 |
PREVASCULARIZED DEVICES AND RELATED METHODS |
摘要 |
The present invention provides an implantable devices for providing a biologically active agent to a subject in need thereof, the device comprising a microvessel construct in contact with a biocompatible, semi-permeable pouch, the pouch encapsulating a cell or cells capable of producing the biologically active agent. The present invention also provides methods for treating or preventing a disorder in a subject using the implantable device. The present invention also provides specific methods for treating or preventing diabetes in a subject comprising implanting in the subject an immunoisolation device comprising a microvessel construct in contact with a biocompatible, semi-permeable pouch, the pouch encapsulating a cell or cells capable of producing a therapeutically effective amount of insulin. Methods for vascularizing and revascularizing tissue, including engineered tissue, are also provided. |
申请公布号 |
WO2006130851(A3) |
申请公布日期 |
2007.07.19 |
申请号 |
WO2006US21542 |
申请日期 |
2006.06.02 |
申请人 |
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA;WILLIAMS, STUART, K.;HOYING, JAMES, B. |
发明人 |
WILLIAMS, STUART, K.;HOYING, JAMES, B. |
分类号 |
A01N65/00;A01N63/00 |
主分类号 |
A01N65/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|