| 发明名称 |
Biaryl linked hydroxamates: preparation and pharmaceutical applications |
| 摘要 |
The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to biaryl containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities. Formula (I), where Z is a single bond or C<SUB>1</SUB>-C<SUB>4 </SUB>hydrocarbon, A is an aromatic ring, B is an aromatic ring.
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| 申请公布号 |
US2007167499(A1) |
申请公布日期 |
2007.07.19 |
| 申请号 |
US20040577219 |
申请日期 |
2004.10.26 |
| 申请人 |
A*BIO PTE LTD. |
发明人 |
STUNKEL WALTER;WANG HAISHAN;YIN ZHENG |
| 分类号 |
A61K31/433;A61K31/34;A61K31/381;A61K31/415;A61K31/4196;A61K31/421;A61K31/4245;A61K31/426;A61K31/427;C07D231/14;C07D261/18;C07D263/32;C07D263/34;C07D277/28;C07D277/40;C07D277/42;C07D277/46;C07D307/54;C07D307/68;C07D333/38;C07D333/70;C07D403/02;C07D405/10;C07D405/12;C07D409/04;C07D409/12;C07D409/14;C07D413/02;C07D417/02;C07D417/04;C07D417/12;C07D417/14 |
主分类号 |
A61K31/433 |
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