METHOD AND APPARATUS FOR HIGH THROUGHPUT DIAGNOSIS OF DISEASED CELLS WITH MICROCHANNEL DEVICES
摘要
<p>The method and apparatus of the present invention detects changes in cell biomechanics caused by any of a variety of diseases and conditions. In one embodiment, the method and apparatus of the invention detect infection of red blood cells. In one embodiment, the invention is a method and apparatus comprising a microfluidic channel with a constriction, for trapping infected red blood cells while allowing healthy red blood cells to deform and pass through the channel. In another embodiment, the invention comprises a suspended microchannel resonator for detecting and counting red blood cells at the constriction of the microfluidic channel.</p>
申请公布号
WO2007081902(A2)
申请公布日期
2007.07.19
申请号
WO2007US00442
申请日期
2007.01.05
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;MANALIS, SCOTT;SURESH, SUBRA;BURG, THOMAS;BABCOCK, KEN
发明人
MANALIS, SCOTT;SURESH, SUBRA;BURG, THOMAS;BABCOCK, KEN