PROLINE-RICH PEPTIDES, PHARMACEUTICAL COMPOSITION, USE OF ONE OR MORE PEPTIDES AND METHOD OF TREATMENT
摘要
The present invention provides oligopeptides with amino acid sequences comprised in set forth in SEQ ID NO 1 to 18, capable of binding to diverse targets, generating increase and sustenance to nitric oxide (NO) production in mammalian cells, potentiate the argininosuccinate synthase activity of animal cells and/or increase the intracellular bivalent calcium ion in animal cells. Also disclosed are pharmaceutical compositions of one or more peptides described in the present invention. The invention further relates to the use of these peptides.
申请公布号
WO2007079558(A2)
申请公布日期
2007.07.19
申请号
WO2007BR00003
申请日期
2007.01.05
申请人
PEP FARMA CONSULTORIA E DESENVOLVIMENTO FARMACEUTICO LTDA;CAMARGO, ANTONIO;IANZER, DANIELLE;SILVA, CARLOS;GOMES, CLAUDIANA;GUERREIRO, JULIANO