| 发明名称 |
METHOD FOR THE TREATMENT OF FIBROSIS USING ANTAGONIST OF THE INTEGRIN ALPHA-4 SUBUNIT |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for treating a subject having a fibrotic condition. <P>SOLUTION: The method comprises administering to a subject having a fibrotic condition, an effective amount of a composition comprising an antibody homolog that antagonizes the interaction of both VLA-4 and alpha 4 beta 7 with their respective alpha-4 ligands or an antibody homolog that antagonizes an interaction of VLA-4 with its ligand or an antibody homolog that antagonizes an interaction of alpha 4 beta 7 with its ligand. <P>COPYRIGHT: (C)2007,JPO&INPIT</p> |
| 申请公布号 |
JP2007182453(A) |
申请公布日期 |
2007.07.19 |
| 申请号 |
JP20070080371 |
申请日期 |
2007.03.26 |
| 申请人 |
BIOGEN IDEC MA INC |
发明人 |
GOTWALS PHILIP;LOBB ROY R;KOTELIANSKY VICTOR |
| 分类号 |
A61K39/395;A61P1/16;A61P9/00;A61P11/00;A61P11/02;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P21/00;A61P25/00;A61P27/02;A61P29/00;A61P37/00;A61P43/00;C07K16/18;C07K16/28;C12N15/09 |
主分类号 |
A61K39/395 |
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