发明名称 |
Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers |
摘要 |
A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered nonsteroidal anti-inflammatory drugs (NSAIDs). The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the NSAID through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery systems for co-administering a hydroxide-releasing agent with an NSAID are provided as well.
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申请公布号 |
US7244447(B2) |
申请公布日期 |
2007.07.17 |
申请号 |
US20030631539 |
申请日期 |
2003.07.30 |
申请人 |
DERMATRENDS, INC. |
发明人 |
HSU TSUNG-MIN;LUO ERIC C. |
分类号 |
A61F13/00;A61K9/00;A61K9/70;A61K31/137;A61K47/02;A61L15/00 |
主分类号 |
A61F13/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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