发明名称 Tubulin inhibitor and process for its preparation
摘要 The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making hemifumarate compounds and compositioning of the present invention.
申请公布号 US7244736(B2) 申请公布日期 2007.07.17
申请号 US20060451078 申请日期 2006.06.12
申请人 WYETH 发明人 BLUM DAVID MICHAEL;WU YANZHONG;SCHMID JEAN;DOYLE TIMOTHY JOHN;AFRAGOLA JAY THOMAS;KU SHERRY MANNCHING;QU FANG FANG
分类号 A61K31/4965;C07D403/00 主分类号 A61K31/4965
代理机构 代理人
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