| 摘要 |
The present invention provides a method of evaluating a sample for ceruloplasmin. The method includes contacting the sample with a multiple immunoaffinity removal medium to result in an unbound fraction which includes the ceruloplasmin. The unbound fraction is subjected to a separation method to provide an aliquot which includes purified ceruloplasmin. The aliquot is then analyzed using ICP-MS to provide a copper ion specific signal; and the sample is evaluated for ceruloplasmin based on the copper ion specific signal.
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