发明名称 |
PREPARATION OF 4,5-DIAMINO-1-(SUBSTITUTED)-PYRAZOLE AND ACID ADDITION SALTS THEREOF |
摘要 |
Disclosed is an improved process for the preparation of 4,5-diamino- 1-(substituted)pyrazoles and acid addition salts thereof by coupling the corresponding 5-amino-1-(substituted)pyrazole with an aromatic diazonium compound to produce an intermediate azo compound and contacting the intermediate azo compound with hydrogen in the presence of a hydrogenation catalyst to produce 4,5-diamino-1-(substituted)pyrazoles. Also disclosed is a decarboxylation process for the preparation of a 5-amino-1-(substituted)pyrazole by heating a solution comprising a 5-amino-4-carboxy-1-(substituted)pyrazole, an inorganic acid and an inert solvent. |
申请公布号 |
WO2007021873(A3) |
申请公布日期 |
2007.07.12 |
申请号 |
WO2006US31272 |
申请日期 |
2006.08.10 |
申请人 |
EASTMAN CHEMICAL COMPANY |
发明人 |
CHAMBERLIN, KIM, STEVEN;KELLY, CHARLES, EVERETTE |
分类号 |
C07D231/38 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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地址 |
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