发明名称 |
Antibodies directed to HER-3 and uses thereof |
摘要 |
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin. |
申请公布号 |
AU2006332065(A1) |
申请公布日期 |
2007.07.12 |
申请号 |
AU20060332065 |
申请日期 |
2006.12.29 |
申请人 |
AMGEN INC.;U3 PHARMA AG |
发明人 |
MIKE ROTHE;ERIC BORGES;SUSANNE HARTMANN;DAN FREEMAN;BOB RADINSKY;MARTIN TREDER |
分类号 |
C07K14/43;A61K39/395;A61P35/00;C07K16/28;C07K16/32 |
主分类号 |
C07K14/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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