发明名称 Method for determining the impact of a multicomponent synthetic product mixture on the biological profile of a disease within a group of living systems and the development of new combinatorial interventions
摘要 The invention provides a method for determining the impact of a chemical multicomponent mixture on the biological profile of a disease comprising the steps of: (a) determining a biological profile of the disease by comparing the biological profile of a group of living systems with symptoms of the disease with the biological profile of a reference (or healthy) group of living systems, using a multivariate analysis; (b) determining the impact of a series of samples of one or more synthetic compositions on the biological profile of the disease, in which samples the concentrations of the one or more synthetic compositions differ, using a multivariate analysis; (c) preparing a set of multicomponent synthetic product mixtures which are expected to display a desired impact on the biological profile of the disease on the basis of the information obtained in step (b); and (d) determining the impact of the set of multicomponent mixtures as prepared in step (c) on the biological profile of the disease using multivariate analysis. The invention also provides a method for preparing a medicament, and the use of a multicomponent synthetic product mixture as prepared in step (c) for preparing a synthetic product-based medicament.
申请公布号 US2007160990(A1) 申请公布日期 2007.07.12
申请号 US20040571087 申请日期 2004.09.03
申请人 WANG MEI;WITKAMP RENGER 发明人 WANG MEI;WITKAMP RENGER
分类号 C12Q1/68;G01N33/50;G01N33/53;G06F19/20;G06Q50/22 主分类号 C12Q1/68
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