| 摘要 |
Devices and methods for improved soli tissue securement are disclosed, in particular, tissue anchoring elements ( 30) and deployment (68) thereol Such tissue anchoring elements may comprise a linkage element (36) and spreading elements (38). Endoscopic devices ( 68) and methods are disclosed for deploying multiple anchoring elements to multiple sites and manipulating at least some of the associated linkage elements to approximate selected sites Applications of such endoscopic devices and methods may include endoluminal therapy such as gastroplasty which may be used for the treatment of obesily and gastroesophageal disease Further aspect of the invention include devices and methods for the modification (44) of mechanical properties of /ones surrounding anchoring sites to decrease the likelihood that anchoring elements will pull out. Such modification may include irritating or injuring the tissue within the zone, thereby causing a healing or scarification response, or may alternatively include deploying a solidifying agent within the zone |
