发明名称 |
Time-domain method and apparatus for determining the depth and concentration of a fluorophore in a turbid medium |
摘要 |
Methods and apparatuses for determining the depth and concentration of fluorophores in a turbid medium are disclosed. The method advantageously provides for a rapid estimation of the depth of the flurophore using characteristics of a temporal point spread function. The concentration of the flurophore can be determined using the method of the present invention by combining a calculated depth of the flurophore with a measurement of the intensity of the emitted fluorescence. The intensity can be accurately measured by the apparatus disclosed herein which combine back-reflection and trans-illumination geometries for the source of light injecting and detection.
|
申请公布号 |
US2007158585(A1) |
申请公布日期 |
2007.07.12 |
申请号 |
US20040577527 |
申请日期 |
2004.10.29 |
申请人 |
ART, ADVANCED RESEARCH TECHNOLOGIES INC. |
发明人 |
HALL DAVID J.;MA GUOBIN;LESAGE FREDERIC;GALLANT PASCAL |
分类号 |
G01N21/64;A61B5/00;G01N21/49 |
主分类号 |
G01N21/64 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|