发明名称 |
COMPOSITIONS COMPRISING MODULATORS OF G-PROTEIN-COUPLED RECEPTOR FOR TREATMENT OF MACULAR DEGENERATION |
摘要 |
The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or ocular inflammation. The methods comprise administering a composition comprising a compound that is an antagonist of a G protein coupled receptor, e.g., the C5a receptor, to a subject in need of treatment or prevention of age-related macular degeneration or another condition involving macular degeneration or ocular neovascularization. The invention provides compositions comprising a compound that is an antagonist of a G protein coupled receptor linked either directly or indirectly to a moiety that binds to a component present on or at the surface of cell or noncellular molecular entity, e.g., a component present in the eye of a subject at risk of or suffering from age related macular degeneration or a related condition or choroidal neovascularization. |
申请公布号 |
WO2006099330(A3) |
申请公布日期 |
2007.07.12 |
申请号 |
WO2006US08960 |
申请日期 |
2006.03.13 |
申请人 |
POTENTIA PHARMACEUTICALS, INC.;DESCHATELETS, PASCAL;FRANCOIS, CEDRIC |
发明人 |
DESCHATELETS, PASCAL;FRANCOIS, CEDRIC |
分类号 |
A61K38/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|