| 发明名称 |
2-PHENYL-2H-PYRAZ0LE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS AND USES THEREOF |
| 摘要 |
A compound having formula (I) wherein R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB> and R<SUB>6</SUB> are defined in the description., is disclosed as an P2X<SUB>7</SUB> antagonist. Methods and compositions for treating disease or condition modulated by P2X<SUB>7</SUB> are also disclosed. |
| 申请公布号 |
WO2007056091(A3) |
申请公布日期 |
2007.07.12 |
| 申请号 |
WO2006US42867 |
申请日期 |
2006.11.02 |
| 申请人 |
ABBOTT LABORATORIES;CARROLL, WILLIAM, A.;PEREZ-MEDRANO, ARTURO;LI, TONGMEI |
发明人 |
CARROLL, WILLIAM, A.;PEREZ-MEDRANO, ARTURO;LI, TONGMEI |
| 分类号 |
C07D231/38;A61K31/415;A61K31/416;A61K31/4162;A61K31/4439;A61P29/00;C07D231/54;C07D401/12;C07D495/04 |
主分类号 |
C07D231/38 |
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