| 摘要 |
Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, and hydrates, thereof, (I) are useful as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, and Z is N or CR<SUB>3</SUB>, and R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, X and Y are as defined herein. |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;VACCARO, WAYNE;CHEN, ZHONG;DODD, DHARMPAL, S.;HUYNH, TRAM, N.;LIN, JAMES;LIU, CHUNJIAN;MUSSARI, CHRISTOPHER, P.;TOKARSKI, JOHN, S.;TORTOLANI, DAVID, R.;WROBLESKI, STEPHEN, T. |
发明人 |
VACCARO, WAYNE;CHEN, ZHONG;DODD, DHARMPAL, S.;HUYNH, TRAM, N.;LIN, JAMES;LIU, CHUNJIAN;MUSSARI, CHRISTOPHER, P.;TOKARSKI, JOHN, S.;TORTOLANI, DAVID, R.;WROBLESKI, STEPHEN, T. |
