The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.
申请公布号
WO2007077028(A2)
申请公布日期
2007.07.12
申请号
WO2006EP12632
申请日期
2006.12.29
申请人
U3 PHARMA AG;AMGEN INC.;ROTHE, MIKE;TREDER, MARTIN;HARTMANN, SUSANNE;FREEMAN, DAN;RADINSKY, BOB
发明人
ROTHE, MIKE;TREDER, MARTIN;HARTMANN, SUSANNE;FREEMAN, DAN;RADINSKY, BOB