Erythropoietin liquid formulation

摘要

A storage-stable liquid erythropoietin (EPO) formulation (A): (i) contains at least four of the amino acids Leu, Ile, Thr, Glu, Asp or Phe; (ii) is free from preservatives, urea and human serum albumen; and (iii) has not been reconstituted from a lyophilizate. An independent claim is also included for a method of preparing (A). ACTIVITY : Antianemic; Nephrotropic. No details of tests for these activities are given. MECHANISM OF ACTION : EPO stimulates formation of erythrocytes in bone marrow.