| 摘要 |
Computer implemented method and apparatus for extracting biologically significant features from cell images such as features located in cell boundary regions and cell-cell junctions. Firstly, an image of one of more cells is segmented to identify cell boundaries for the individual cells in the image. Next, one or more boundary regions (such as free or contact periphery regions) for the individual cells in the image are defined based on the identified cell boundaries. Finally, one or more cell features are characterized within the one or more defined boundary regions. The cells may be hepatocyte cells. The extracted features may be correlated with particular conditions induced by biologically-active agents with which cells have been treated. |
