Pyrimidines as PLK inhibitors

摘要

The present invention comprises compounds of general formula (1) wherein A, X, Y, Z, R^a, R^b, R^c, R¹, R² and R³ are defined as in claim 1 , which are suitable for the treatment of diseases characterised by excessive or anomalous cell proliferation, and the use thereof for preparing a pharmaceutical composition with the above-mentioned properties.