发明名称 |
PYRIMIDO[5,4-D]PYRIMIDINES, MEDICAMENTS COMPRISING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR THEIR PREPARATION |
摘要 |
The present invention relates to pyrimido[5,4-d]pyrimidines of the general formula (see formula I) in which R a to R c are as defined in Claim 1, their tautomers, their stereoisomers and their salts, in particular their physiologically tolerated salts with inorganic or organic acids or bases which have valuable pharmacological properties, in particular an inhibiting action on signal transduction mediated by tyrosine kinases, their use for the treatment of diseases, in particular tumour diseases, and their preparation.
|
申请公布号 |
CA2199401(C) |
申请公布日期 |
2007.07.10 |
申请号 |
CA19952199401 |
申请日期 |
1995.09.05 |
申请人 |
DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
METZ, THOMAS;DAHMANN, GEORG;VON RUDEN, THOMAS;HIMMELSBACH, FRANK |
分类号 |
C07D487/04;A61K31/505;A61K31/535;A61K31/55;A61K31/675;A61P7/00;A61P9/00;A61P17/06;A61P29/00;A61P35/00;A61P37/00;C07D519/00;C07F9/547;C07F9/6561 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|