摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a photoaged model human skin and model animal each useful for evaluating effect of cosmetics to preventing and improving photoageing, etc., and to provide a method for preparing those. <P>SOLUTION: The method for preparing the photoaged human skin comprises continuously irradiating ultraviolet light having 80-100 mJ/cm<SP>2</SP>B wavelength for 4-8 weeks to a transplanted skin of immunodeficient nonhuman animal to which human skin is transplanted and allow the irradiated skin to stand at least for three weeks after irradiation. The human photoageing model skin and the model animal are each prepared by the method. <P>COPYRIGHT: (C)2007,JPO&INPIT</p> |